Fact-checking Sidenote by AsapSCIENCE – Hemorrhoids: you will likely get one, so what do you do?

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Hemorrhoids are more than just a common discomfort; they are a health issue that affects millions yet is often shrouded in misconceptions. This duality of prevalence and stigma contributes to a range of misunderstandings regarding their causes, symptoms, and effective treatment options. In the latest episode of the Sidenote podcast by AsapSCIENCE, hosts dive deep into the world of hemorrhoids, unraveling the myths and shedding light on the science behind this frequently encountered ailment. In this blog post, we will meticulously fact-check the claims made during that enlightening discussion, ensuring you are equipped with accurate, research-backed insights. Whether you are presently managing hemorrhoids or simply wish to educate yourself on how to potentially avoid them, join us as we explore the scientific realities behind this often downplayed health concern.

Fact Check Analysis

Claim

Squatty potties help with hemorrhoids.

Veracity Rating: 2 out of 4

Facts

## Evaluating the Claim: Squatty Potties Help with Hemorrhoids

The claim that Squatty Potties can help with hemorrhoids is based on the idea that using these devices promotes a more natural squatting position during bowel movements, which may reduce straining and pressure on the anal region. This section will evaluate the validity of this claim using scientific and academic references.

### Physiological Basis

Squatty Potties work by elevating the feet during bowel movements, mimicking a squatting position. This position is believed to relax the puborectalis muscle, straighten the rectum, and facilitate easier and more complete emptying of the bowels[1][4]. Theoretically, this could reduce straining, which is a common factor associated with the development and exacerbation of hemorrhoids[3][5].

### Evidence on Squatty Potties and Hemorrhoids

While there is some anecdotal evidence and theoretical support for the idea that squatting can reduce straining and potentially alleviate hemorrhoids, the scientific evidence is not conclusive. Studies specifically examining the effect of squatting or using Squatty Potties on hemorrhoids are limited and often ambiguous[2]. For instance, a review of studies on squatting for defecation notes that the relationship between squatting and hemorrhoids remains unresolved due to mixed findings and the influence of social factors on toilet technology[2].

### Benefits of Squatting Position

Squatting during bowel movements is often described as a more natural position that can reduce straining and improve bowel evacuation[1][3]. This position may help prevent or alleviate conditions like hemorrhoids by reducing pressure on the anal veins. However, the direct link between using Squatty Potties and the prevention or treatment of hemorrhoids is not strongly supported by scientific evidence.

### Conclusion

While Squatty Potties may help reduce straining during bowel movements by promoting a squatting position, which could theoretically benefit individuals with hemorrhoids, the claim that they specifically help with hemorrhoids lacks robust scientific evidence. The available literature suggests that squatting can make defecation easier and potentially reduce straining, but it does not conclusively demonstrate a direct benefit for hemorrhoid prevention or treatment[1][2][3]. Therefore, the claim should be viewed with caution, and individuals should consult healthcare professionals for personalized advice on managing hemorrhoids.

### Recommendations

For individuals suffering from hemorrhoids, lifestyle changes such as increasing fiber intake, staying hydrated, and maintaining regular physical activity are recommended[1]. Medical treatments like rubber band ligation or sclerotherapy may also be necessary in more severe cases. While Squatty Potties may be a useful tool for improving bowel habits, they should not be relied upon as the sole method for managing hemorrhoids without consulting a healthcare provider.

Citations


Claim

New habits only begin truly forming within 59 to 66 days and can take up to 335 days to establish.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: New Habits Forming Within 59 to 66 Days and Taking Up to 335 Days to Establish

The claim that new habits begin forming within 59 to 66 days and can take up to 335 days to establish is supported by recent scientific research. Here's a detailed analysis of the claim based on available evidence:

### Evidence Supporting the Claim

1. **Phillippa Lally's Study**: A seminal study by Phillippa Lally and her team at University College London found that, on average, it takes about 66 days for a new behavior to become automatic, though the range can vary significantly from 18 to 254 days[1][3]. This study provides a foundational understanding of habit formation timelines.

2. **University of South Australia Research**: A systematic review conducted by researchers at the University of South Australia found that new habits can begin forming within about two months (median of 59-66 days) but can take up to 335 days to establish[2]. This research aligns with the claim and highlights the variability in habit formation times.

3. **Variability in Habit Formation**: Both studies emphasize that the time required to form a habit can vary widely depending on the complexity of the behavior, personal motivation, and individual circumstances[1][2][3]. This variability supports the notion that while some habits may form relatively quickly, others may require more time.

### Conclusion

Based on the evidence from reputable sources, the claim that new habits begin forming within 59 to 66 days and can take up to 335 days to establish is **valid**. The scientific consensus supports the idea that habit formation is a process that can vary significantly among individuals and behaviors.

### Recommendations for Habit Formation

– **Consistency**: Regular practice is crucial for habit formation.
– **Motivation**: Enjoying the activity or having a strong reason to perform it can enhance habit formation.
– **Planning**: Incorporating new habits into daily routines, such as morning or evening practices, can increase success rates[2][3].

Overall, while the claim is supported by scientific evidence, it's essential to recognize that individual experiences may vary, and patience is key when attempting to form new habits.

Citations


Claim

50% of people will get hemorrhoids by the age of 50.

Veracity Rating: 3 out of 4

Facts

## Claim Evaluation: "50% of people will get hemorrhoids by the age of 50"

To evaluate the claim that "50% of people will get hemorrhoids by the age of 50," we need to consider available scientific evidence and prevalence data on hemorrhoids.

### Prevalence of Hemorrhoids

– **General Prevalence**: Hemorrhoids are common, but the exact prevalence is difficult to determine because many cases are asymptomatic, and individuals may not seek medical attention[1][2]. Studies suggest that between 60% to 70% of Canadians will experience hemorrhoids at some point in their lifetime[2].

– **Age-Specific Prevalence**: The peak prevalence of hemorrhoids occurs between the ages of 45 and 65[1][2]. However, specific data on the prevalence by the age of 50 is less clear.

– **Claim Specificity**: The claim that "50% of people will get hemorrhoids by the age of 50" is supported by a statement from the Mayo Clinic Press, which mentions that "one in two people will experience a hemorrhoid by the time they reach 50"[4]. This aligns with the general understanding that hemorrhoids are very common, especially as people age.

### Scientific Evidence

– **Studies and Data**: While there is no specific study cited that directly supports the exact figure of 50% by age 50, the prevalence of hemorrhoids is known to increase with age. For instance, a study found that 38.93% of participants suffered from hemorrhoids, with most being asymptomatic[3]. Another source indicates that at least 50% of people over 50 will experience hemorrhoids[2].

– **Risk Factors**: Factors such as obesity, pregnancy, and low-fiber diets contribute to the development of hemorrhoids[1][2]. These factors can influence the likelihood of experiencing hemorrhoids by a certain age.

### Conclusion

The claim that "50% of people will get hemorrhoids by the age of 50" is plausible based on the general prevalence of hemorrhoids and their increased occurrence with age. While specific studies directly confirming this exact figure are not cited, the available evidence supports the notion that hemorrhoids are common and their prevalence increases significantly as people age. Therefore, the claim is generally supported by the broader context of hemorrhoid prevalence.

**Evidence Summary**:
– **Prevalence**: Hemorrhoids are common, affecting a significant portion of the population, especially as people age.
– **Age-Specific Data**: Peak prevalence occurs between ages 45 and 65, with increased likelihood in older individuals.
– **Claim Support**: The Mayo Clinic Press mentions that one in two people will experience hemorrhoids by age 50, aligning with the claim.

**Sources**:
– [1] AAFP: Hemorrhoids: Diagnosis and Treatment Options
– [2] Canadian Digestive Health Foundation: Hemorrhoids
– [3] PubMed: The prevalence of hemorrhoids in adults
– [4] Mayo Clinic Press: Who's the queen of hemorrhoids?

Citations


Claim

In 1990, 10 million people in the United States complained of hemorrhoids, corresponding to a prevalence rate of 4.4% of the population.

Veracity Rating: 2 out of 4

Facts

## Evaluation of the Claim

The claim states that in 1990, 10 million people in the United States complained of hemorrhoids, corresponding to a prevalence rate of 4.4% of the population. To assess the validity of this claim, we need to examine available data on the prevalence of hemorrhoids during that time period.

### Available Data

– **Prevalence of Hemorrhoids**: Hemorrhoids are indeed a common condition, affecting a significant portion of the population. According to more recent data, about 75% of people will experience hemorrhoids at some point in their lives, and approximately 10.4 million people in the United States have hemorrhoids, which corresponds to about 4.4% of the general population[1]. However, this data does not specifically reference the year 1990.

– **Historical Prevalence**: There is limited specific data available for the exact prevalence of hemorrhoids in the United States in 1990. The claim seems to align with the general understanding that hemorrhoids are common, but without precise historical data from 1990, it's challenging to confirm the exact figures.

### Conclusion

While the claim that 10 million people in the United States complained of hemorrhoids in 1990, corresponding to a prevalence rate of 4.4%, aligns with the general understanding of hemorrhoid prevalence, there is no specific data from 1990 to directly support this claim. The prevalence of hemorrhoids is well-documented in more recent years, but historical data from 1990 is not readily available in the provided sources.

### Recommendations for Further Research

To validate the claim, further research should focus on historical medical literature or epidemiological studies from the late 1980s to early 1990s. This could involve searching through archives of medical journals or databases that track health trends and disease prevalence over time.

### Summary

In summary, while the claim about the prevalence of hemorrhoids in 1990 is plausible given the general prevalence of the condition, it cannot be confirmed without specific historical data. The discussion around hemorrhoids highlights their commonality and the importance of addressing them through lifestyle changes and medical treatments, but precise historical prevalence figures require more detailed historical research.

Citations


Claim

A meta-analysis found that hemorrhoids are most common in white people and those who are socioeconomically affluent.

Veracity Rating: 2 out of 4

Facts

## Evaluation of the Claim

The claim suggests that a meta-analysis found hemorrhoids to be most common in white people and those who are socioeconomically affluent. To assess the validity of this claim, we need to examine available scientific literature and epidemiological studies related to hemorrhoids.

### Prevalence and Demographics

1. **Prevalence of Hemorrhoids**: Hemorrhoids are a common anorectal condition, with a reported prevalence ranging from 4.4% to 36.4% of the general population, peaking between ages 45 and 65[1][3].

2. **Demographic Patterns**: A study based on data from the United States, England, and Wales found that whites are affected more frequently than blacks by hemorrhoids. Additionally, higher socioeconomic status was associated with increased prevalence rates of hemorrhoids[2]. However, this study does not specifically mention a meta-analysis supporting these findings.

3. **Socioeconomic Factors**: The relationship between socioeconomic status and hemorrhoid prevalence is noted in some studies, suggesting that higher socioeconomic status may be linked to a higher prevalence of hemorrhoids, contrasting with the epidemiology of constipation[2].

### Conclusion

While there is evidence suggesting that hemorrhoids are more prevalent in white individuals and those with higher socioeconomic status, the claim specifically references a meta-analysis as the source of this information. However, the provided sources do not mention a meta-analysis supporting these demographic patterns. Therefore, the claim about a meta-analysis is not directly supported by the available literature.

**Recommendation**: For a more accurate assessment, it would be beneficial to locate the specific meta-analysis mentioned in the claim or to rely on broader epidemiological studies that detail demographic patterns in hemorrhoid prevalence.

**Summary of Findings**:
– **Prevalence**: Hemorrhoids affect approximately 4.4% of the U.S. adult population, peaking between ages 45 and 65[1][2].
– **Demographics**: Whites are more frequently affected than blacks, and higher socioeconomic status is associated with increased prevalence[2].
– **Claim Validation**: The claim about a meta-analysis is not supported by the provided sources.

Citations


Claim

Females tend to have hemorrhoids at a higher rate, especially if they have had children.

Veracity Rating: 2 out of 4

Facts

## Evaluation of the Claim: Females Tend to Have Hemorrhoids at a Higher Rate, Especially if They Have Had Children

The claim that females tend to have hemorrhoids at a higher rate, especially if they have had children, requires careful examination. Hemorrhoids are a common condition affecting both men and women, with various factors contributing to their development.

### Prevalence of Hemorrhoids in Men and Women

Hemorrhoids do not typically affect one gender more than the other in terms of overall prevalence. However, women are more likely to report hemorrhoids to their doctors than men, which might create a perception of higher prevalence among women[1][3]. Approximately 75% of adults will experience hemorrhoids at some point in their lives, with about half of all people having them by age 50[2][3].

### Impact of Pregnancy and Childbirth

Pregnancy and childbirth are significant risk factors for developing hemorrhoids in women. The increased pressure on the veins in the pelvic area during pregnancy and the strain of childbirth can lead to hemorrhoid formation[2][3]. This suggests that women who have had children might be more likely to experience hemorrhoids due to these specific factors.

### Other Risk Factors

Both men and women can develop hemorrhoids due to various factors, including:

– **Straining during bowel movements**
– **Chronic constipation or diarrhea**
– **Sitting for long periods**
– **Obesity**
– **Family history of hemorrhoids**
– **Age (more common between 45 and 65 years old)**[2][3].

### Conclusion

While the claim that females tend to have hemorrhoids at a higher rate, especially if they have had children, is partially supported by the increased risk during pregnancy and childbirth, it is not entirely accurate to say that women have a higher overall prevalence of hemorrhoids than men. The perception of higher prevalence in women might be influenced by reporting behaviors and specific risk factors like pregnancy. Both genders are equally susceptible to hemorrhoids, and various lifestyle and physiological factors contribute to their development.

**Evidence Summary:**

– **Prevalence:** Hemorrhoids affect both genders equally, with about 75% of adults experiencing them at some point[3].
– **Pregnancy and Childbirth:** These are significant risk factors for women[2][3].
– **Reporting Behavior:** Women are more likely to report hemorrhoids to doctors[1][3].
– **Risk Factors:** Apply to both genders, including straining, constipation, and age[2][3].

Citations


Claim

Certain people can have increased vascularization in the anus, which could potentially be genetic, leading to a higher likelihood of hemorrhoids.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: Genetic Factors in Hemorrhoids

The claim suggests that certain people may have increased vascularization in the anus due to genetic factors, which could increase their likelihood of developing hemorrhoids. To evaluate this claim, we need to examine the role of genetics in hemorrhoid development, particularly focusing on vascular structure and its potential genetic influences.

### Genetic Component of Hemorrhoids

1. **Genetic Predisposition**: Research indicates that there is a genetic component to developing hemorrhoids. Studies have shown that individuals with a family history of hemorrhoids are more likely to develop them, suggesting a possible genetic predisposition[1][2][4].

2. **Vascular Structure and Genetics**: Certain genetic factors can affect the structural integrity of blood vessels, making them more susceptible to swelling and inflammation, which are key factors in hemorrhoid development[2][4]. This implies that genetic variations could influence vascular health and potentially lead to increased vascularization or vulnerability in the anal region.

3. **Genomic Studies**: A large international study identified over 100 regions in the human genome associated with the risk of developing hemorrhoids. These regions are linked to smooth muscle function, epithelial, and connective tissue, which are crucial for maintaining the integrity of the anal and rectal tissues[5].

### Conclusion

The claim that genetic factors could lead to increased vascularization in the anus, potentially increasing the likelihood of hemorrhoids, is supported by evidence. Genetic predispositions can affect the strength and structure of blood vessels and other tissues relevant to hemorrhoid development. While lifestyle factors are also significant, the genetic component plays a role in susceptibility to hemorrhoids.

### Recommendations for Further Research

– **Genetic Variants and Vascular Health**: Further studies could focus on specific genetic variants that affect vascular health and their impact on hemorrhoid risk.
– **Polygenic Risk Models**: Utilizing polygenic risk models, as mentioned in recent studies, could help predict individual risk based on genetic data and potentially inform preventive measures[5].

In summary, while the claim is supported by existing research, continued investigation into the genetic factors influencing vascular health and hemorrhoid risk would provide more detailed insights.

Citations


Claim

A study indicated that diarrhea, rather than constipation, may be a more significant cause of hemorrhoids.

Veracity Rating: 2 out of 4

Facts

## Evaluation of the Claim: Diarrhea as a More Significant Cause of Hemorrhoids Than Constipation

The claim suggests that diarrhea, rather than constipation, may be a more significant cause of hemorrhoids. This assertion challenges traditional assumptions that often link constipation with an increased risk of developing hemorrhoids. To evaluate this claim, we will examine relevant scientific studies and evidence.

### Evidence Supporting the Claim

1. **Case-Control Study**: A study published in the context of a case-control analysis involving 325 patients who underwent proctoscopy found that diarrhea, but not constipation, was associated with an increased risk of hemorrhoids. Specifically, the odds ratio for diarrhea was 2.1 (95% CI: 1.2-3.7), indicating a significant association[1].

### Contrasting Evidence

1. **Cross-Sectional Study**: Another study involving 2,813 participants who underwent colonoscopy found that constipation was associated with an increased risk of hemorrhoids. The odds ratio for constipation was 1.43 (95% CI: 1.11, 1.86), suggesting that constipation is indeed a risk factor[3].

2. **IBS and Hemorrhoids**: Research on irritable bowel syndrome (IBS) indicates that both constipation and diarrhea can contribute to the development of hemorrhoids due to straining during bowel movements and prolonged sitting on the toilet[4][5].

### Conclusion

The claim that diarrhea may be a more significant cause of hemorrhoids than constipation is supported by some studies, such as the case-control study mentioned[1]. However, other research suggests that constipation is also a significant risk factor[3]. The relationship between bowel habits and hemorrhoids is complex, and both diarrhea and constipation can contribute to their development, particularly in the context of conditions like IBS[4][5]. Therefore, while the claim has some basis, it should be understood within the broader context of hemorrhoid risk factors.

### Recommendations for Future Research

– **Comprehensive Studies**: Further studies should aim to comprehensively assess the impact of both diarrhea and constipation on hemorrhoid development, considering other factors like diet, lifestyle, and underlying health conditions.
– **Mechanistic Insights**: Investigating the physiological mechanisms by which diarrhea and constipation influence hemorrhoid formation could provide deeper insights into prevention and treatment strategies.

In summary, while there is evidence supporting the role of diarrhea as a risk factor for hemorrhoids, constipation remains a recognized risk factor as well. Both conditions can contribute to the development of hemorrhoids, and their impact should be considered in the context of overall bowel health and lifestyle factors.

Citations


Claim

Historically, the first mention of hemorrhoids was found in Egyptian scriptures from 1700 BC.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: "Historically, the first mention of hemorrhoids was found in Egyptian scriptures from 1700 BC."

The claim that the first mention of hemorrhoids was found in Egyptian scriptures from 1700 BC is supported by historical evidence. According to Wikipedia, the first known mention of hemorrhoids is indeed from an Egyptian papyrus dating back to around 1700 BC. This papyrus advises using an ointment made from acacia leaves to treat a painful perianal condition, which is likely hemorrhoids[1].

### Evidence and Historical Context

1. **Egyptian Papyrus (1700 BC):** The papyrus suggests a treatment involving an ointment made from acacia leaves, indicating that the Egyptians were aware of hemorrhoids and had developed treatments for them[1][3].

2. **Ancient Civilizations:** Hemorrhoids have been documented in other ancient civilizations, including the Greeks and Romans. Hippocrates, a Greek physician, discussed treatments for hemorrhoids around 460 BC, which included ligation and excision techniques[1][3].

3. **Historical Treatments:** Over time, various treatments have evolved, from ancient methods like ligation and cauterization to modern procedures such as rubber band ligation and sclerotherapy[3][5].

### Conclusion

The claim that the first mention of hemorrhoids was found in Egyptian scriptures from 1700 BC is **valid** based on historical records. These early mentions highlight the long-standing awareness and management of hemorrhoids across different cultures and time periods.

### Additional Information

– **Prevalence and Management:** Hemorrhoids affect a significant portion of the population, with about 50% of individuals experiencing them by age 50. Management strategies include lifestyle changes, such as increased fiber intake, and medical procedures like rubber band ligation[3].

– **Societal Stigma:** Despite their commonality, hemorrhoids are often subject to societal stigma, which can hinder open discussions about the condition. Encouraging humor and health awareness can help mitigate this stigma[3].

Citations


Claim

Clinical studies show fiber supplements reduce the risk of symptoms and bleeding by 50%.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: Fiber Supplements Reduce Symptoms and Bleeding by 50%

The claim that fiber supplements reduce the risk of symptoms and bleeding by 50% is supported by clinical studies, particularly in the context of hemorrhoids. Here's a detailed analysis based on available scientific evidence:

### Evidence from Clinical Studies

1. **Hemorrhoids Treatment**: Clinical trials have shown that fiber supplements are effective in managing symptoms and bleeding associated with hemorrhoids. A meta-analysis of seven trials involving 378 patients demonstrated that fiber significantly reduced the risk of persistent symptoms by 47% and bleeding by 50% compared to non-fiber controls[1][5]. This aligns with the claim, indicating a substantial benefit of fiber in reducing bleeding.

2. **Mechanism and Benefits**: The benefits of fiber in gastrointestinal health are well-documented. Fiber helps improve stool consistency, reduce constipation, and alleviate symptoms of irritable bowel syndrome (IBS)[2]. For hemorrhoids, these effects can reduce strain during bowel movements, potentially decreasing the risk of bleeding and discomfort.

3. **Specific Studies on Hemorrhoids**: A study focusing on internal bleeding hemorrhoids found that adding dietary fiber reduced the number of bleeding episodes over time, though the effect was not immediate[3]. This suggests that while fiber may not provide immediate relief, it can offer long-term benefits in managing hemorrhoid symptoms.

### Conclusion

The claim that fiber supplements reduce the risk of symptoms and bleeding by 50% is supported by clinical evidence, particularly in the context of hemorrhoids. Studies consistently show that fiber has a beneficial effect on reducing bleeding and improving symptoms associated with hemorrhoids[1][5]. However, it's essential to note that individual results may vary, and fiber's effectiveness can depend on the type of fiber, dosage, and individual health conditions.

### Recommendations

– **Dietary Changes**: Increasing dietary fiber intake through whole foods or supplements can be beneficial for managing hemorrhoids.
– **Consultation**: Individuals should consult healthcare professionals before starting any new supplements to ensure they are appropriate for their specific condition.

In summary, the claim is supported by scientific evidence, highlighting the importance of fiber in managing hemorrhoid symptoms and reducing bleeding.

Citations


Claim

This pill decreased the risk of bleeding by 67% and persistent pain by 65%.

Veracity Rating: 1 out of 4

Facts

To evaluate the claim that a pill, specifically micro ionized purified flavonoid fraction (MPFF), decreases the risk of bleeding by 67% and persistent pain by 65% in patients with hemorrhoids, we need to examine existing scientific literature and clinical trials.

## Claim Evaluation

1. **Bleeding Reduction**: The claim suggests a 67% reduction in bleeding risk. While MPFF has been shown to be effective in reducing bleeding associated with hemorrhoids, specific percentages like 67% are not commonly cited in the literature. A meta-analysis indicated that MPFF significantly reduced bleeding, with an odds ratio (OR) of 0.082 (95% CI 0.027-0.250; P < 0.001) for this symptom[2]. However, this does not directly translate to a 67% reduction.

2. **Pain Reduction**: The claim also mentions a 65% reduction in persistent pain. While MPFF has been reported to decrease pain, the specific percentage of 65% is not documented in the available literature. Studies have shown that MPFF tends to decrease pain, though not always significantly[2][4].

## Supporting Evidence

– **MPFF Efficacy**: MPFF, also known as Daflon, is a venoactive drug that has been widely used to treat hemorrhoids. It has been shown to improve symptoms such as bleeding, pain, pruritus, and discharge[2][4]. However, the specific percentages mentioned in the claim are not directly supported by the available scientific literature.

– **Clinical Trials**: While numerous studies have demonstrated the benefits of MPFF in managing hemorrhoidal symptoms, the exact figures of 67% for bleeding and 65% for pain are not explicitly mentioned in these studies. A randomized trial with 1,514 patients is mentioned in the claim, but such a specific study is not identified in the provided search results.

## Conclusion

The claim that MPFF decreases the risk of bleeding by 67% and persistent pain by 65% in patients with hemorrhoids is not directly supported by the available scientific literature. While MPFF is known to be effective in reducing these symptoms, the specific percentages mentioned are not documented in the reviewed studies. Therefore, the claim appears to be an exaggeration or misinterpretation of the actual benefits of MPFF in treating hemorrhoids. For precise efficacy figures, further review of specific clinical trials or studies would be necessary.

Citations


Claim

Preparation H isn't just like this cure but it might help with your symptoms and even if it's placebo and you feel better use it.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: Preparation H for Hemorrhoid Symptoms

The claim suggests that Preparation H may help alleviate hemorrhoid symptoms, even if its effectiveness is debated or if the relief is due to a placebo effect. To evaluate this claim, we'll examine the available evidence regarding Preparation H's efficacy in managing hemorrhoid symptoms.

### Mechanism of Action

Preparation H contains phenylephrine, a vasoconstrictor that temporarily narrows blood vessels, reducing swelling and discomfort associated with hemorrhoids[3][5]. This mechanism provides relief from symptoms such as itching, burning, and pain[5].

### Efficacy in Symptom Relief

Preparation H is widely used for its ability to provide temporary relief from hemorrhoid symptoms. It helps shrink swollen hemorrhoids, which can soothe itching and discomfort for several hours[3]. While it does not cure hemorrhoids, it is effective in managing symptoms[3].

### Placebo Effect Consideration

The placebo effect refers to the phenomenon where patients experience improvement in symptoms due to their belief in the treatment's efficacy, rather than the treatment itself. While the claim mentions that even if Preparation H's relief is due to a placebo effect, it can still be beneficial if the patient feels better. This perspective acknowledges that subjective improvement in symptoms can be valuable, even if not entirely due to the active ingredients.

### Scientific Evidence

A study on Preparation H's effect on wound healing in rectal ulcers suggests that it may enhance healing rates, though the difference was not statistically significant[1]. This study indicates potential benefits beyond just symptom relief, though more research is needed to confirm these findings.

### Conclusion

The claim that Preparation H can help with hemorrhoid symptoms, even if its efficacy is debated or due to a placebo effect, is supported by evidence. Preparation H is known to provide temporary relief from symptoms like itching and discomfort by shrinking swollen hemorrhoids[3][5]. While it may not cure hemorrhoids, its ability to manage symptoms makes it a useful over-the-counter treatment option. Additionally, the placebo effect can contribute to perceived benefits, making it a viable choice for symptom relief.

**Recommendation**: For individuals experiencing hemorrhoid symptoms, Preparation H can be considered as part of a broader management strategy that includes lifestyle changes and other treatments as needed. However, it's crucial to consult a healthcare provider if symptoms persist or worsen.

Citations


Claim

There was a newer treatment called PP 110 gel that was more effective than Preparation H.

Veracity Rating: 4 out of 4

Facts

## Evaluation of the Claim: PP 110 Gel vs. Preparation H

The claim suggests that PP 110 Gel is a newer treatment option for hemorrhoids that has been shown to be more effective than Preparation H. To verify this claim, we need to examine the available scientific evidence and studies comparing these two treatments.

### Evidence Supporting the Claim

1. **Clinical Study**: A prospective, randomized, open-label study compared PP 110 Gel with Preparation H in treating hemorrhoids. The study found that PP 110 Gel was significantly better than Preparation H in reducing bleeding, providing pain relief, and controlling itching—three common symptoms of hemorrhoids[1][3][5]. Specifically, PP 110 Gel showed improvements of 6% in bleeding, 10% in pain relief, and 11% in itching control compared to Preparation H[1].

2. **Formulation and Delivery Mechanism**: PP 110 Gel contains the same active ingredients as Preparation H (pramoxine 1% and phenylephrine 0.25%) but utilizes a novel film-forming agent. This agent creates a protective film that ensures prolonged contact of the active ingredients with the affected tissue, leading to a longer therapeutic effect[3][5]. This formulation allows for once-daily application, which is more convenient than the three-to-four times daily application required for Preparation H[3].

### Conclusion

Based on the available evidence, the claim that PP 110 Gel is more effective than Preparation H in treating hemorrhoids is supported by clinical studies. These studies demonstrate that PP 110 Gel offers superior symptom relief and convenience due to its innovative delivery system.

### Recommendations for Future Verification

– **Long-term Studies**: While PP 110 Gel shows promise in short-term symptom management, long-term efficacy and safety studies would further validate its effectiveness.
– **Comparative Analysis with Other Treatments**: Comparing PP 110 Gel with other hemorrhoid treatments, including phlebotonics and surgical options, could provide a broader understanding of its place in hemorrhoid management.

Overall, the claim is substantiated by existing research, but ongoing evaluation and comparison with other treatments will be beneficial for comprehensive assessment.

Citations


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